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The Scientific World Journal
Volume 2012, Article ID 486324, 4 pages
Research Article

Effect of Isosporiasis Prevention with Toltrazuril on Long-Term Pig Performance

1Division of Infectious Diseases and Veterinary Administration, Department of Epizootiology with Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Grunwaldzki Square 45, 50-366 Wrocław, Poland
2Division of Infectious Diseases and Epidemiology, Department of Large Animal Diseases, Faculty of Veterinary Medicine, Warsaw University of Life Sciences—SGGW, Nowoursynowska 159c, 02-776 Warsaw, Poland
3Divison of Parasitology, Department of Internal Diseases with Clinic of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Agricultural University of Wrocław, Poland
4Bayer HealthCare Animal Health, Leverkusen, Germany

Received 10 October 2011; Accepted 16 November 2011

Academic Editor: Kunio Ohmiya

Copyright © 2012 K. Rypula et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The efficacy of toltrazuril treatment was assessed in two experiments in Polish swine herds. Experiment 1 included a toltrazuril treatment group, Group A ( 𝑛 = 4 1 0 ), and untreated control, Group B ( 𝑛 = 3 8 6 ). Time to sale in Group A was 108 days versus 120 days for Group B, with average body weights at sale of 114.2 kg and 108.8 kg, respectively ( 𝑃 < 0 . 0 5 ). In experiment 2, the health status and body weight gain of 238 piglets treated with toltrazuril (Group D) were compared to 235 untreated piglets (Group K). A similar difference was observed in average body weights of slaughtered animals, being on average 104 kg in Group D and 101 kg in Group K ( 𝑃 < 0 . 0 1 ). Animals from Group D were slaughtered 5 days earlier than animals from Group K (day 166 versus day 171). Data from clinical trials suggest treatment of coccidiosis with toltrazuril offering potential for improved animal welfare and yields, however this has remained unproven in field conditions in large swine production facilities. The present study confirms the efficacy of toltrazuril treatment when used in the field and the subsequent positive impact on time to weaning, time to market, and on weight gain at all time points.