The Effects of α-Lipoic Acid against Testicular Ischemia-Reperfusion Injury in Rats

Table 1

The effect of ischemia-reperfusion (2 h torsion 720° in a clockwise direction and 2 h detorsion of the testis) and LA (100 mg/kg ip, 30 minutes prior to detorsion) on MSTD, Johnsen’s score and germ cell apoptosis.

	MSTD (μm)	Johnsen’s score	% TUNEL
(1) Control; (n = 7)	281.03±4.82	9.66±0.05	0.87±0.04
(2) Sham; (n = 7)	275.37±5.89	9.46±0.7	0.96±0.05
(3) I (n = 7)	220.62±2.81^∗	6.51±0.09^∗	3.32±0.05^∗
(4) I/R; (n = 7)	217.17±3.37^∗	6.40±0.08^∗	3.49±0.03^∗
(5) I/R + LA; (n = 7)	260.18±2.97^∗∗	8.04±0.09^∗∗	1.90±0.03^∗∗

Values are mean ± SEM.
* P < 0.05 compared with the control and sham group.
** P < 0.05 compared with the I and I/R group.