Research Article

Assessment of Control Tissue for Gene and Protein Expression Studies: A Comparison of Three Alternative Lung Sources

Table 4

Biomarkers unsuitable for gene and protein expression studies in cancer resection, transplant biopsy, and pneumothorax.

Cancer resectionTransplant biopsyPneumothorax

Gene expressionVEGFA, PGF, FLT1, KDR, MMP-2, MMP-9, TIMP-1, TIMP-2NoneNone
Protein expression
Bronchial liningVEGFA, TIMP-1, KDR, MMP-2KDR, TIMP-2None
Alveolar liningTIMP-1MMP-2VEGFA
MacrophagesPGFMMP-2, VEGFAVEGFA