Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study
Table 2
The hemodynamic variables of sympathetic vasomotor response and their corresponding changes at baseline and after inspiratory cough.
MSA ()
Control ()
value: MSA versus control (Mann-Whitney Test)
Baseline
Pulsatility index
5.3 ± 3.4‡
4.4 ± 2.5‡
0.464
(cm/s)
39.0 ± 11.4‡
46.2 ± 19.0‡
0.356
(cm/s)
−0.5 ± 4.5‡
0.5 ± 6.4‡
0.436
(cm/s)
10.1 ± 5.6‡
14.1 ± 10.2‡
0.408
(cm/s)
5.2 ± 3.1‡
7.0 ± 5.2‡
0.436
Flow amount (mL/min)
20.8 ± 17.6‡
30.8 ± 31.2‡
0.494
Diameter (mm)
2.7 ± 0.4
2.7 ± 0.5
0.944
Heart rate (beat/min)
79.6 ± 14.2
73.0 ± 9.7‡
0.249
After inspiratory cough
Pulsatility index
7.8 ± 2.2‡
8.1 ± 2.0‡
0.654
(cm/s)
33.3 ± 9.8‡
35.6 ± 12.9‡
0.654
(cm/s)
−7.1 ± 2.9‡
−7.2 ± 3.5‡
0.906
(cm/s)
4.8 ± 3.7‡
5.5 ± 2.3‡
0.944
(cm/s)
2.6 ± 0.9‡
2.7 ± 1.0‡
0.944
Flow amount (mL/min)
8.4 ± 5.2‡
8.4 ± 4.8‡
0.944
Diameter (mm)
2.4 ± 0.4
2.4 ± 0.3
0.981
Heart rate (beat/min)
80.1 ± 14.4
78.6 ± 8.5‡
0.981
Difference between baseline and after inspiratory cough
Pulsatility index
2.5 ± 1.7
3.6 ± 1.8
0.133
Δ (cm/s)
5.7 ± 5.7
10.6 ± 10.9
0.454
Δ (cm/s)
6.5 ± 5.3
7.7 ± 5.2
0.654
Δ (cm/s)
5.2 ± 4.2
8.5 ± 8.8
0.621
Δ (cm/s)
2.5 ± 2.3
4.3 ± 4.5
0.524
ΔFlow amount (mL/min)
12.0 ± 13.0
22.4 ± 26.9
0.408
ΔDiameter (mm)
0.2 ± 0.4
0.2 ± 0.4
0.832
ΔHeart rate (beat/min)
0.4 ± 3.0*
5.5 ± 4.0*
0.001*
Latency (s)
5.1 ± 0.8*
3.9 ± 0.8*
0.000*
Note: Values are mean ± S.D.; MSA: multiple system atrophy; ‡ or * indicated significant difference of hemodynamic measurements between baseline and after inspiratory cough or between MSA and control, respectively.
