Table 1: Patients’ demographics and mean symptom frequency grade, clinical measure outcomes, and DTS grade.


Number of subjects ( )29635
Age (mean ± SD)
Clinical measures (data from worse eye)
(mean ± SD)
 TBUT (seconds)
 Schirmer’s test I (mm)
 Corneal staining:
  (i) superior
  (ii) inferior
  (iii) nasal
  (iv) temporal
  (v) central
DED symptom frequency (mean ± SD)
 Sensitivity to light
 Gritty sensation
 Burning sensation
 Episodic blur vision
 Fluctuating vision with blinking 0.9 ± 1.4
 Pain on waking up in morning
 Need for artificial tear use
DTS grade