Research Article
Robust Optimization of Alginate-Carbopol 940 Bead Formulations
Table 4
Experimental layout using a orthogonal array and results obtained in every run.
| Run | | AUC | EE | SR | SF | Dm | | Mean | | Mean | | Mean | | Mean | | Mean | | Mean | |
| 1 | | 73.00 | 28.82 | 268.68 | 49.11 | 48.43 | 37.04 | 2863.78 | 69.14 | 0.52 | −5.74 | 1.34 | −2.71 | | 2 | | 50.00 | 27.96 | 421.78 | 49.29 | 54.88 | 38.26 | 1937.37 | 65.74 | 0.20 | −13.88 | 1.47 | −3.43 | | 3 | | 69.33 | 35.57 | 117.23 | 48.60 | 53.63 | 38.08 | 1320.67 | 62.42 | 0.25 | −12.06 | 1.53 | −3.70 | | 4 | | 91.33 | 31.94 | 461.89 | 48.23 | 54.88 | 38.17 | 1681.62 | 64.51 | 0.58 | −4.77 | 1.72 | −2.96 | | 5 | | 102.33 | 32.18 | 405.74 | 48.66 | 59.00 | 38.92 | 2177.52 | 66.76 | 0.27 | −11.32 | 1.64 | −4.50 | | 6 | | 198.33 | 25.60 | 348.62 | 47.04 | 53.51 | 38.08 | 1119.52 | 60.98 | 0.65 | −3.83 | 1.69 | −4.61 | | 7 | | 118.67 | 19.17 | 354.48 | 48.22 | 54.34 | 38.21 | 1610.31 | 64.14 | 0.30 | −10.47 | 1.51 | −3.65 | | 8 | | 293.33 | 28.10 | 257.57 | 46.46 | 54.46 | 38.24 | 1082.83 | 60.69 | 0.25 | −12.01 | 1.54 | −3.73 | | 9 | | 106.00 | 18.80 | 427.85 | 47.90 | 57.14 | 38.65 | 1459.06 | 63.28 | 0.55 | −5.26 | 1.66 | −4.42 | | 10 | | 60.00 | 24.77 | 448.50 | 48.89 | 59.73 | 39.04 | 2786.18 | 68.90 | 0.19 | −14.68 | 2.07 | −6.33 | | 11 | | 82.67 | 22.18 | 634.32 | 48.71 | 59.33 | 38.97 | 1151.14 | 61.22 | 0.26 | −11.95 | 1.83 | −5.27 | | 12 | | 119.33 | 40.29 | 401.70 | 47.93 | 56.07 | 38.49 | 3685.23 | 71.32 | 0.55 | −5.20 | 1.57 | −3.97 | | 13 | | 111.67 | 23.30 | 1326.03 | 47.92 | 58.83 | 38.91 | 1868.79 | 65.39 | 0.40 | −9.30 | 1.73 | −5.12 | | 14 | | 148.67 | 36.17 | 225.15 | 47.45 | 59.88 | 39.06 | 3003.21 | 69.55 | 0.20 | −13.88 | 1.72 | −4.70 | | 15 | | 209.33 | 36.72 | 469.47 | 47.14 | 59.49 | 39.00 | 2017.31 | 66.10 | 0.38 | −8.50 | 1.56 | −4.01 | | 16 | | 238.67 | 40.29 | 1052.68 | 46.04 | 53.97 | 38.15 | 3094.41 | 69.81 | 0.35 | −9.26 | 1.67 | −4.54 | | 17 | | 142.00 | 32.25 | 536.70 | 48.08 | 56.39 | 38.52 | 1554.57 | 63.83 | 0.34 | −9.40 | 1.41 | −3.04 | | 18 | | 138.33 | 33.61 | 841.84 | 47.79 | 60.02 | 39.08 | 1420.16 | 63.05 | 0.26 | −11.71 | 2.81 | −8.99 | |
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