Clinical Study

CD4+CD25highCD127low Regulatory T Cells in Peripheral Blood Are Not an Independent Factor for Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation

Figure 3

Lymphocyte subpopulations and Treg within different time periods from HSCT. Box plots graphs of lymphocyte subpopulation frequencies in the three patient cohorts and in normal controls. The grafts show the dispersion around the median. The line across each box represents the median for patients in cohort 1 ( 𝑛 = 2 6 , median time from HSCT 244 days), in cohort 2 ( 𝑛 = 2 2 , median time from HSCT 510 days), in cohort 3 ( 𝑛 = 3 6 , median time from HSCT 720 days), and for normal controls ( 𝑛 = 2 0 ). The bottom edge is the first quartile and the top edge is the third quartile, the error bars represent the dispersion within the 95% confidence interval, the dots represent extreme values. Differences between the groups were explored using the Mann-Whitney U-test. Significant differences between the groups are shown above ( 𝑃 < 0 . 0 5 ). All other differences between the median values were not significant ( 𝑃 > 0 . 0 5 ). CD: cluster of differentiation.
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