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The Scientific World Journal
Volume 2012, Article ID 616934, 7 pages
http://dx.doi.org/10.1100/2012/616934
Research Article

Analysis of the Volumes of the Posterior Cranial Fossa, Cerebellum, and Herniated Tonsils Using the Stereological Methods in Patients with Chiari Type I Malformation

1Department of Radiology, Kayseri Education and Research Hospital, 38010 Kayseri, Turkey
2Department of Anatomy, Erciyes University School of Medicine, 38039 Kayseri, Turkey
3Department of Radiology, ElazฤฑฤŸ Harput State Hospital, 23200 ElazฤฑฤŸ, Turkey

Received 13 December 2011; Accepted 22 January 2012

Academic Editors: J. G. Eriksen and A. Youk

Copyright © 2012 Ümit Erkan Vurdem et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. The aim of this study was to determine the posterior cranial fossa volume, cerebellar volume, and herniated tonsillar volume in patients with chiari type I malformation and control subjects using stereological methods. Material and Methods. These volumes were estimated retrospectively using the Cavalieri principle as a point-counting technique. We used magnetic resonance images taken from 25 control subjects and 30 patients with chiari type I malformation. Results. The posterior cranial fossa volume in patients with chiari type I malformation was significantly smaller than the volume in the control subjects (๐‘ƒ<0.05). In the chiari type I malformation group, the cerebellar volume was smaller than the control group, but this difference was not statistically significant (๐‘ƒ>0.05). In the chiari type I malformation group, the ratio of cerebellar volume to posterior cranial fossa volume was higher than in the control group. We also found a positive correlation between the posterior cranial fossa volume and cerebellar volume for each of the groups (๐‘Ÿ=0.865, ๐‘ƒ<0.001). The mean (ยฑSD) herniated tonsillar volume and length were 0.89ยฑ0.50โ€‰cm3 and 9.63ยฑ3.37โ€‰mm in the chiari type I malformation group, respectively. Conclusion. This study has shown that posterior cranial fossa and cerebellum volumes can be measured by stereological methods, and the ratio of these measurements can contribute to the evaluation of chiari type I malformation cases.