Review Article
A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers
Table 14
Pharmacokinetic parameters of ampicillin, norfloxacin, and in combination with piperine after oral treatment in rabbit [
95].
| | Treatment | (h) | (μg/mL) | (h) | AUC (μg·h/mL) |
| | Ampicillin (150 mg/kg) | 1 ± 0.31 | 44.6 ± 0.27 | 1.3 ± 0.46 | 103.7 ± 0.52 | Ampicillin (150 mg/kg)
+ piperine (20 mg/kg) | 1.1 ± 0.3 | 251.2 ± 0.28 | 1.9 ± 0.57 | 350.49 ± 0.47 | | Norfloxacin (150 mg/kg) | 3.1 ± 0.32 | 11 ± 0.26 | 1.75 ± 0.38 | 63.98 ± 0.51 | | Norfloxacin (150 mg/kg) + piperine (20 mg/kg) | 3.2 ± 0.31 | 16.1 ± 0.27 | 2.97 ± 0.38 | 111.69 ± 0.54 |
|
|
n = 6, mean ± SD, P < 0.05.
|
