A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers

Table 16

Comparison of plasma concentrations (μg/mL) of gatifloxacin- and gatifloxacin + piperine-treated birds after single oral administration (10 mg/kg) [101].

Time (h)	Gatifloxacin	Gatifloxacin + piperine
0.5	0.48 ± 0.013	0.53 ± 0.009**
0.75	1 ± 0.014	1.16 ± 0.029**
1	1.35 ± 0.016	1.46 ± 0.021*
2	1.74 ± 0.023	2.14 ± 0.020
4	1.35 ± 0.02	1.47 ± 0.034*
8	0.97 ± 0.009	1.08 ± 0.019**
12	0.46 ± 0.01	0.54 ± 0.008

n = 6, *Significant at P < 0.05, **Highly significant at P < 0.01.