Review Article
A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers
Table 21
Enhancement of antibiotic activity by niaziridin* in combination with antibiotics against different organisms [
145,
146].
| | Organisms | Antibiotics | Concentration (μg/mL) | Fold enhancement of activity |
| | E. coli (CA8000) | Rifampicin | 20.0 | 38.8 | | Rifampicin | 30.0 | 12.6 | | Ampicillin | 6.0 | 5.3 | | Tetracycline | 1.0 | 2.3 | | Tetracycline | 2.0 | 5.2 | | Nalidixic acid | 6.0 | 50.0 | | B. subtilis (MTCC121) | Rifampicin | 0.05 | 19.4 | | Ampicillin | 0.01 | 5.1 | | Tetracycline | 1.0 | 3.5 | | Nalidixic acid | 2.0 | 7.0 | | M. smegmatis (MC2 155) | Rifampicin | 0.05 | 1.9 | | Ampicillin | 0.01 | 4.7 | | Tetracycline | 1.0 | 4.0 | | Nalidixic acid | 2.0 | 1.2 |
|
|
*Dose: E. coli = 0.1 μg/kg; B. subtilis and M. smegmatis = 1.0 μg/kg.
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