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The Scientific World Journal
Volume 2012, Article ID 650707, 6 pages
http://dx.doi.org/10.1100/2012/650707
Clinical Study

Screening for Depression, Sleep-Related Disturbances, and Anxiety in Patients with Adenocarcinoma of the Pancreas: A Preliminary Study

1Department of Biomedical and Health Information Sciences, University of Illinois at Chicago, 1919 W Taylor Street MC 530, Chicago, IL 60612, USA
2Department of Radiation Oncology, Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA
3University of Michigan Hospital Social Work, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA
4University of Michigan Hospital Cancer Center-Pancreatic Clinic, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA
5Center for Human Genetics, Division of Medical Genetics, Department of Medicine, Duke University Medical Center, P.O. Box 3445, 905 LaSalle Street, Durham, NC 27710, USA
6Molecular and Behavioral Neuroscience Institute, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA
7Department of Radiation Oncology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA
8Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA
9Departments of Surgery and Molecular and Integrative Physiology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA
10Department of Biostatistics, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA
11Department of Psychiatry, University of Michigan, 1500 East Medical Center Drive, Room F6236 MCHC, P.O. Box 0295, Ann Arbor, MI 48109-0295, USA

Received 14 February 2012; Accepted 14 March 2012

Academic Editors: J. Haukka, G. Moreno-Bueno, and H. Zitzelsberger

Copyright © 2012 Andrew D. Boyd et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose. Screening for depression, sleep-related disturbances, and anxiety in patients with diagnosed adenocarcinoma of the pancreas. Materials and Methods. Patients were evaluated at initial consultation and subsequent visits at the multidisciplinary pancreatic cancer clinic at our University Cancer Center. Cross-sectional and longitudinal psychosocial distress was assessed utilizing Personal Health Questionnaire 9 (PHQ9) to screen for depression and monitor symptoms, the Penn State Worry Questionnaire (PSWQ) for generalized anxiety, and the University of Michigan Sleep Questionnaire to monitor sleep symptoms. Results. Twenty-two patients diagnosed with pancreatic cancer participated during the 6-month pilot study with longitudinal followup for thirteen patients. In this study, mild-to-moderate depressive symptoms, anxiety, and potential sleep problems were common. The main finding of the study was 23% of the patients who were part of this pilot project screened positive for moderately severe major depressive symptoms, likely anxiety disorder or a potential sleep disorder during the study. One patient screened positive for moderately severe depressive symptoms in longitudinal followup. Conclusions. Depression, anxiety, and sleep problems are evident in patients with pancreatic cancer. Prospective, longitudinal studies, with larger groups of patients, are needed to determine if these comorbid symptoms impact outcome and clinical course.