Low-Dose Fluvastatin Prevents the Functional Alterations of Endothelium Induced by Short-Term Cholesterol Feeding in Rabbit Carotid Artery

Figure 4

The effects of inhibition of nitric oxide synthesis by LNA and cyclooxygenase inhibition by INDO on the contractile responses to serotonin in isolated rabbit carotid artery. Figures from control group (a, d), cholesterol group (b, e), and cholesterol + fluvastatin group (c, f). Ring presentations of carotid arteries from −LNA or −INDO (○) (𝑛=5) and +LNA or +INDO (•) (𝑛=5) in the groups. Values are expressed as means ± S.E.M. *𝑃<0.05 compared with −LNA and +LNA or −INDO and +INDO in the groups, Wilcoxon paired signed ranks test.

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