Novel Computational Methodologies for Structural Modeling of Spacious Ligand Binding Sites of G-Protein-Coupled Receptors: Development and Application to Human Leukotriene B4 Receptor

<table>Ligand-receptor docking score (GOLD score) when docking with known agonists and antagonists of BLT1. Open squares show docking scores of known BLT1 agonists. Filled triangles show docking scores of known BLT1 antagonists. PubChem ID of BLT1 agonists (descending order): 5280492, 5280745, 5283156, 5280876, 5283129, 5280877. PubChem ID of BLT1 antagonists (descending order): 159476, 3081307, 6444688, 6439064, 6449854, 6540750, 132425, 6439436, 115100, 6442838, 204055, 177941, 196905, 192617.</table>

The Scientific World Journal

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Figure 5

Figure 5: Novel Computational Methodologies for Structural Modeling of Spacious Ligand Binding Sites of G-Protein-Coupled Receptors: Development and Application to Human Leukotriene B4 Receptor 

Figure 5 | Novel Computational Methodologies for Structural Modeling of Spacious Ligand Binding Sites of G-Protein-Coupled Receptors: Development and Application to Human Leukotriene B4 Receptor 