Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas
Figure 3
(a and b) Immunoreactivity of β-catenin (upper row) and β-catenin-P654 (lower row) in astrocytic gliomas of WHO grade II (left), WHO grade III (middle), and WHO gradeIV (right). Scale bars represent 100 μm. (c and d) Note that β-catenin immunoreactivity was significantly augmented with increasing WHO grade (c) while β-catenin-P654 expression significantly decreased in high-grade tumours (d). Columns indicate categories of staining frequencies.
