The Scientific World Journal / 2012 / Article / Fig 3

Research Article

Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas

Figure 3

(a and b) Immunoreactivity of β-catenin (upper row) and β-catenin-P654 (lower row) in astrocytic gliomas of WHO grade II (left), WHO grade III (middle), and WHO gradeIV (right). Scale bars represent 100 μm. (c and d) Note that β-catenin immunoreactivity was significantly augmented with increasing WHO grade (c) while β-catenin-P654 expression significantly decreased in high-grade tumours (d). Columns indicate categories of staining frequencies.

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