The Scientific World Journal

Research Article

Synthesis and Neuropharmacological Evaluation of Some Novel Quinoxaline 2, 3-Dione Derivatives

Table 4

Beam walk test.
GroupsDistance walkedTotal time taken to walkFalling timeFecal pellets
Control 2 0 9 . 5 ± 0 . 2 0 8 2 300 1 2 7 . 6 ± 0 . 0 5 7 1 ± 0
Ethidium
Bromide 3 5 . 4 7 ± 0 . 2 9 0 6 300 1 6 6 . 5 ± 0 . 2 9 ** 5 . 7 6 ± 0 . 3 9 **
Antioxidant 1 7 1 . 6 ± 0 . 7 9 2 8 *** 300 1 4 2 . 8 ± 0 . 5 8 ** 1 . 6 ± 0 . 2 4 ***
Comp2a 1 4 2 . 5 ± 0 . 1 4 3 5 *** 300 1 1 1 . 4 ± 0 . 1 7 0 * 1 . 4 ± 0 . 2 4 ***
Comp2b 1 5 8 . 4 ± 0 . 1 4 7 *** 300 9 2 . 3 ± 0 . 8 0 3 *** 1 . 2 ± 0 . 2 ***
Comp2c 1 3 7 . 4 ± 0 . 1 2 .8***300 1 1 8 . 3 ± 0 . 0 8 1 6 *** 1 . 6 ± 0 . 2 4 ***
𝑃 < 0 . 0 5 ; ***extremely significant; **moderately significant; *significant.