Research Article

Acute Effects of Vardenafil on Pulmonary Artery Responsiveness in Pulmonary Hypertension

Table 2

Monocrotaline-induced morphometric changes in pulmonary arteries. Results are expressed as mean ± s.e. mean. *Significantly different from control rat at 𝑃 < 0 . 0 5 . Number of animals is indicated in parentheses. WT: media wall thickness; ED: external diameter.

Control ( 𝑛 = 1 5 )MCT ( 𝑛 = 1 6 )

WT ( 𝜇 )9.7 ± 0.519.2 ± 1.2*
ED ( 𝜇 )84 ± 695 ± 5
% WT21.1 ± 1.243.1 ± 1.1*