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The Scientific World Journal
Volume 2012 (2012), Article ID 718791, 12 pages
http://dx.doi.org/10.1100/2012/718791
Research Article

A Study on Solubilization of Poorly Soluble Drugs by Cyclodextrins and Micelles: Complexation and Binding Characteristics of Sulfamethoxazole and Trimethoprim

General Chemistry Division, Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Marmara University, Uskudar, 34668 Istanbul, Turkey

Received 22 October 2011; Accepted 7 December 2011

Academic Editors: Y. V. Nageswar and P. Zakeri-Milani

Copyright © 2012 Sinem Göktürk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [15 citations]

The following is the list of published articles that have cited the current article.

  • Filomena Silva, Ana Figueiras, Eugenia Gallardo, Cristina Nerín, and Fernanda C. Domingues, “Strategies to improve the solubility and stability of stilbene antioxidants: a comparative study between cyclodextrins and bile acids,” Food Chemistry, 2013. View at Publisher · View at Google Scholar
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  • Sinem Gokturk, and Sebahat Aslan, “Study on Binding Properties of Poorly Soluble Drug Trimethoprim in Anionic Micellar Solutions,” Journal of Dispersion Science and Technology, vol. 35, no. 1, pp. 84–92, 2014. View at Publisher · View at Google Scholar
  • Debarati Ray, Animesh Pramanik, and Nikhil Guchhait, “Differential modulation of lactim-lactam tautomerism process of an isoindole fused imidazole system in three different micellar assemblies of varying surface charge: a spectroscopic approach to various photophysical properties,” Rsc Advances, vol. 4, no. 26, pp. 13256–13265, 2014. View at Publisher · View at Google Scholar
  • Debarati Ray, Ashis Kundu, Animesh Pramanik, and Nikhil Guchhait, “Exploring the Interaction of a Micelle Entrapped Biologically Important Proton Transfer Probe with the Model Transport Protein Bovine Serum Albumin,” Journal Of Physical Chemistry B, vol. 119, no. 6, pp. 2168–2179, 2015. View at Publisher · View at Google Scholar
  • Mustafa Ulvi Gürbüz, Ali Serol Ertürk, and Metin Tülü, “Synthesis of surface-modified TREN-cored PAMAM dendrimers and their effects on the solubility of sulfamethoxazole (SMZ) as an analog antibiotic drug,” Pharmaceutical Development and Technology, vol. 22, no. 5, pp. 678–689, 2016. View at Publisher · View at Google Scholar
  • V. S. Tyukova, S. A. Kedik, A. V. Panov, E. S. Zhavoronok, and M. S. Zolotareva, “Preparation and Molecular Composition of an Inclusion Complex of Dilsulfiram and Hydroxypropyl-beta-Cyclodextrin,” Pharmaceutical Chemistry Journal, vol. 50, no. 1, pp. 38–43, 2016. View at Publisher · View at Google Scholar
  • Sabyasachi Chatterjee, and Gopinatha Suresh Kumar, “Visualization of Stepwise Drug–Micelle Aggregate Formation and Correlation with Spectroscopic and Calorimetric Results,” The Journal of Physical Chemistry B, 2016. View at Publisher · View at Google Scholar
  • Stopková, Oremusová, Hriňaková, Bezáková, Andriamanty, and Žufková, “Influence of Valsartan on the thermodynamics of micellization of anionic surfactant Sodium Dodecyl Sulphate,” European Pharmaceutical Journal, vol. 63, no. 2, pp. 30–36, 2016. View at Publisher · View at Google Scholar
  • Neng Qiu, Xuebing Li, and Junda Liu, “Application of cyclodextrins in cancer treatment,” Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2017. View at Publisher · View at Google Scholar
  • Mohammad A. Altamimi, and Steven H. Neau, “Investigation of the in vitro performance difference of drug-Soluplus® and drug-PEG 6000 dispersions when prepared using spray drying or lyophilization,” Saudi Pharmaceutical Journal, vol. 25, no. 3, pp. 419–439, 2017. View at Publisher · View at Google Scholar
  • Ryota Shiozawa, Yutaka Inoue, Isamu Murata, and Ikuo Kanamoto, “Effect of antioxidant activity of caffeic acid with cyclodextrins using ground mixture method,” Asian Journal of Pharmaceutical Sciences, 2017. View at Publisher · View at Google Scholar