A Study on Solubilization of Poorly Soluble Drugs by Cyclodextrins and Micelles: Complexation and Binding Characteristics of Sulfamethoxazole and Trimethoprim

<table>(a) The absorbance change of <svg height="14.5" id="M46" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 65.824997 14.5" width="65.824997" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,14.5)">
<g transform="translate(72,-60.4)">
<text transform="matrix(1,0,0,-1,-71.95,60.76)">
<tspan style="font-size: 12.50px; " x="0" y="0">4</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="9.3772497" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="18.404415" y="0">×</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="35.433502" y="0">0</tspan>
</text>
<text transform="matrix(1,0,0,-1,-30.26,65.93)">
<tspan style="font-size: 8.75px; " x="0" y="0">−</tspan>
<tspan style="font-size: 8.75px; " x="5.99512" y="0">5</tspan>
</text>
</g>
</g>
</svg> M TMP with the concentrations of CDs. (b) The absorbance change of <svg height="14.5" id="M47" style="vertical-align:-0.3135pt" version="1.1" viewbox="0 0 65.824997 14.5" width="65.824997" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,14.5)">
<g transform="translate(72,-60.4)">
<text transform="matrix(1,0,0,-1,-71.95,60.76)">
<tspan style="font-size: 12.50px; " x="0" y="0">4</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="9.3772497" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="18.404415" y="0">×</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="35.433502" y="0">0</tspan>
</text>
<text transform="matrix(1,0,0,-1,-30.26,65.93)">
<tspan style="font-size: 8.75px; " x="0" y="0">−</tspan>
<tspan style="font-size: 8.75px; " x="5.99512" y="0">5</tspan>
</text>
</g>
</g>
</svg> M SMX with the concentrations of CDs.</table>

The Scientific World Journal

fig4

Figure 4

Figure 4: A Study on Solubilization of Poorly Soluble Drugs by Cyclodextrins and Micelles: Complexation and Binding Characteristics of Sulfamethoxazole and Trimethoprim 

Figure 4 | A Study on Solubilization of Poorly Soluble Drugs by Cyclodextrins and Micelles: Complexation and Binding Characteristics of Sulfamethoxazole and Trimethoprim 