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The Scientific World Journal
Volume 2012, Article ID 718791, 12 pages
Research Article

A Study on Solubilization of Poorly Soluble Drugs by Cyclodextrins and Micelles: Complexation and Binding Characteristics of Sulfamethoxazole and Trimethoprim

General Chemistry Division, Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Marmara University, Uskudar, 34668 Istanbul, Turkey

Received 22 October 2011; Accepted 7 December 2011

Academic Editors: Y. V. Nageswar and P. Zakeri-Milani

Copyright © 2012 Sinem Göktürk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Inclusion complex formation of TMP/ g–CD and SMX/ b–CD (Figure 1) and micellar solubilization of TMP and SMX by SDS micelles (Figure 2).

  1. Supplementary Figure 1
  2. Supplementary Figure 2