Clinical Characteristics of Recurrent Nasopharyngeal Carcinoma in High-Incidence Area

Table 3

Comparison of tumor invasion in patients with pNPC* and rNPC.

Tumor invasion	No invasion in rNPC (case)	Invasion in rNPC (case)	P value
Oropharynx			<0.01
No invasion in pNPC (case)	157	31
Invasion in pNPC (case)	66	20
Nasal cavity			0.81
No invasion in pNPC (case)	189	37
Invasion in pNPC (case)	34	14
Soft palate			<0.01
No invasion in pNPC (case)	265	9
Invasion in pNPC (case)	0	0
Prestyloid space			<0.01
No invasion in pNPC (case)	52	32
Invasion in pNPC (case)	105	85
Carotid sheath area			<0.01
No invasion in pNPC (case)	114	41
Invasion in pNPC (case)	80	39
Pterygopalatine fossa			<0.01
No invasion in pNPC (case)	230	30
Invasion in pNPC (case)	10	4
Skull base			<0.01
No invasion in pNPC (case)	114	102
Invasion in pNPC (case)	16	42
Anterior group of cranial nerve			<0.01
No invasion in pNPC (case)	186	65
Invasion in pNPC (case)	10	13
Posterior group of cranial nerve			<0.01
No invasion in pNPC (case)	259	13
Invasion in pNPC (case)	2	0
Paranasal sinuses			<0.01
No invasion in pNPC (case)	194	54
Invasion in pNPC (case)	15	11
Infratemporal fossa			<0.01
No invasion in pNPC (case)	256	15
Invasion in pNPC (case)	3	0
Orbital apex			0.03
No invasion in pNPC (case)	255	14
Invasion in pNPC (case)	4	1
Cavernous sinus			<0.01
No invasion in pNPC (case)	197	60
Invasion in pNPC (case)	8	9
Cervical vertebrae			0.06
No invasion in pNPC (case)	269	5
Invasion in pNPC (case)	0	0
Intracranial			<0.01
No invasion in pNPC (case)	238	33
Invasion in pNPC (case)	1	2
Laryngopharynx			0.50
No invasion in pNPC (case)	272	2
Invasion in pNPC (case)	0	0

*Primary nasopharyngeal carcinoma (total 274 patients had clear radiographic image data).