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The Scientific World Journal
Volume 2012 (2012), Article ID 738423, 9 pages
Research Article

Computational Methods to Work as First-Pass Filter in Deleterious SNP Analysis of Alkaptonuria

1Department of Biotechnology, Faculty of Biomedical Sciences, Technology & Research, Sri Ramachandra University, Chennai 600116, India
2Centre for Nanobiotechnology, Medical Biotechnology Division, School of Biosciences and Technology, VIT University, Tamil Nadu, Vellore 632014, India

Received 13 September 2011; Accepted 31 October 2011

Academic Editor: Andrew Walley

Copyright © 2012 R. Magesh and C. George Priya Doss. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • C. George Priya Doss, B. Rajith, R. Magesh, and A. Ashish Kumar, “Influence of the SNPs on the structural stability of CBS protein: Insight from molecular dynamics simulations,” Frontiers in Biology, 2014. View at Publisher · View at Google Scholar
  • C. George Priya Doss, and R. Magesh, “Computational Identification of Pathogenic Associated nsSNPs and its Structural Impact in UROD Gene: A Molecular Dynamics Approach,” Cell Biochemistry and Biophysics, 2014. View at Publisher · View at Google Scholar
  • Nagaraja M. Phani, Shreeshakala Acharya, Seethu Xavy, Nalini Bhaskaranand, Manoj K. Bhat, Aditya Jain, Padmalatha S. Rai, and Satyamoorthy Kapaettu, “Genetic association of KCNJ10 rs1130183 with seizure susceptibility and computational analysis of deleterious non-synonymous SNPs of KCNJ10 gene,” Gene, vol. 536, no. 2, pp. 247–253, 2014. View at Publisher · View at Google Scholar
  • David J Timson, “Value of predictive bioinformatics in inherited metabolic diseases,” World Journal of Medical Genetics, vol. 5, no. 3, pp. 46, 2015. View at Publisher · View at Google Scholar
  • Babajan Banaganapalli, Kaleemuddin Mohammed, Imran Ali Khan, Jumana Y. Al-Aama, Ramu Elango, and Noor Ahmad Shaik, “A Computational Protein Phenotype Prediction Approach to Analyze the Deleterious Mutations of Human MED12 Gene,” Journal of Cellular Biochemistry, vol. 117, no. 9, pp. 2023–2035, 2016. View at Publisher · View at Google Scholar
  • Fatima A. Morad, Omran M. Rashidi, Saida S. Sadath, Faisal A. Al-Allaf, Mohammad Athar, Mohamed N. Alama, Sherif E. Edris, Nabeel S. Bondagji, Noor A. Shaik, Babajan Banaganapalli, and Zuhier Awan, “In Silico Approach to Investigate the Structural and Functional Attributes of Familial Hypercholesterolemia Variants Reported in the Saudi Population,” Journal of Computational Biology, 2017. View at Publisher · View at Google Scholar