The Relationship between Coenzyme Q10, Oxidative Stress, and Antioxidant Enzymes Activities and Coronary Artery Disease
Table 2
Correlations between plasma coenzyme Q10 and the ratios of coenzyme Q10 to lipid profiles, lipid peroxidation, and antioxidant enzyme activities after adjusting for the potential confounders.
Plasma coenzyme Q10 (μmol/L)
Coenzyme Q10/TC (μmol/mmol)
Coenzyme Q10/TG (μmol/mmol)
Coenzyme Q10/LDL-C (μmol/mmol)
( value)
MDA (μmol/L)
Model 12
−0.72 (<0.05)
−3.81 (0.03)
−0.22 (0.30)
−2.16 (0.02)
Model 23
−0.02 (0.96)
−0.69 (0.70)
−0.01 (0.97)
−0.02 (0.99)
Model 34
−0.06 (0.87)
−0.75 (0.68)
0.02 (0.93)
−0.00 (1.00)
CAT (U/mg protein)
Model 1
99.23 (<0.01)
502.66 (<0.01)
46.72 (0.03)
276.78 (<0.01)
Model 2
54.09 (0.13)
293.29 (0.08)
26.74 (0.19)
137.34 (0.16)
Model 3
44.31 (0.22)
233.31 (0.18)
16.24 (0.47)
115.06 (0.25)
SOD (U/mg protein)
Model 1
−14.77 (<0.01)
−63.53 (<0.01)
−8.95 (<0.01)
−38.12 (<0.01)
Model 2
−12.51 (<0.01)
−51.66 (0.01)
−7.87 (<0.01)
−32.15 (<0.01)
Model 3
−12.16 (<0.01)
−50.85 (0.01)
−8.31 (<0.01)
−32.20 (<0.01)
GPx (U/mg protein)
Model 1
2.22 (<0.01)
8.45 (0.04)
0.69 (0.15)
5.02 (0.02)
Model 2
0.08 (0.92)
−1.50 (0.69)
−0.11 (0.79)
−1.89 (0.39)
Model 3
0.03 (0.98)
−1.58 (0.69)
−0.34 (0.47)
−2.04 (0.37)
1Regression coefficient (). 2None adjusted. 3Adjusted for age and gender. 4Same as for model 2 and also adjusted for systolic blood pressure, waist to hip ratio, creatinine, and smoking. CAT: catalase activity; GPx: glutathione peroxidase; LDL-C: low density lipoprotein-cholesterol; MDA: malondialdehyde; SOD: superoxide dismutase; TC: total cholesterol; TG: triglyceride.
