Clinical Study

The Relationship between Coenzyme Q10, Oxidative Stress, and Antioxidant Enzymes Activities and Coronary Artery Disease

Table 3

The odds ratios of coronary artery disease based on the concentrations of coenzyme Q10 and the ratios of coenzyme Q10 to the lipid profiles.

Odds ratio (95% CI) 𝑃 value

Coenzyme Q10 < 0.52 μmol/L1.00
Coenzyme Q10 ≥ 0.52 μmol/L
 Model 110.08 (0.02–0.36)<0.01
 Model 220.11 (0.11–0.90)0.04
 Model 330.03 (0.00–0.49)0.01
Coenzyme Q10/TC < 0.10 μmol/mmol1.00
Coenzyme Q10/TC ≥ 0.10 μmol/mmol
 Model 10.14 (0.05–0.43))<0.01
 Model 20.24 (0.04–1.56)0.14
 Model 30.27 (0.04–1.91)0.19
Coenzyme Q10/TG < 0.52 μmol/mmol1.00
Coenzyme Q10/TG ≥ 0.52 μmol/mmol
 Model 10.19 (0.07–0.52)<0.01
 Model 20.03 (0.00–0.35)<0.01
 Model 30.03 (0.00–0.51)0.02
Coenzyme Q10/LDL-C < 0.18 μmol/mmol1.00
Coenzyme Q10/LDL-C ≥ 0.18 μmol/mmol
 Model 10.10 (0.03–0.35)<0.01
 Model 20.05 (0.01–0.47)<0.01
 Model 30.06 (0.01–0.62)0.02

1None adjusted.
2Adjusted for age and gender.
3Same as for model 2 and also adjusted for systolic blood pressure, waist to hip ratio, creatinine and smoking.
CI: confidence interval; LDL-C: low density lipoprotein-cholesterol; TC: total cholesterol; TG: triglyceride.