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The Scientific World Journal
Volume 2012 (2012), Article ID 793039, 6 pages
http://dx.doi.org/10.1100/2012/793039
Research Article

Review Analysis of the Association between the Prevalence of Activated Brown Adipose Tissue and Outdoor Temperature

1Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan
2Department of Information Engineering, I-Shou University, Kaohsiung, Taiwan
3Department of Medical Imaging and Radiological Sciences, I-Shou University, Kaohsiung 82445, Taiwan
4Department of Nuclear Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70428, Taiwan

Received 25 November 2011; Accepted 21 December 2011

Academic Editors: A. A. Romanovsky and A. M. Valverde

Copyright © 2012 Yung-Cheng Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Brown adipose tissue (BAT) is important for regulating body weight. Environmental temperature influences BAT activation. Activated BAT is identifiable using 1 8 F -fluorodeoxyglucose positron emission tomography/computed tomography ( 1 8 F -FDG PET/CT). 1 8 F -FDG PET/CT scans done between June 2005 and May 2009 in our institution in tropical southern Taiwan and BAT studies from PubMed (2002–2011) were reviewed, and the average outdoor temperatures during the study periods were obtained. A simple linear regression was used to analyze the association between the prevalence of activated BAT ( 𝑃 ) and the average outdoor temperature ( 𝑇 ). The review analysis for 9 BAT studies ( 𝑛 = 1 6 , 7 6 5 ) showed a significant negative correlation ( 𝑟 = 0 . 7 4 1 , 𝑃 = 0 . 0 2 2 ) between the prevalence of activated BAT and the average outdoor temperature. The equation of the regression line is 𝑃 ( % ) = 6 . 9 9 0 . 2 0 × 𝑇 ( C ) . The prevalence of activated BAT decreased by 1% for each 5 C increase in average outdoor temperature. In a neutral ambient temperature, the prevalence of activated BAT is low and especially rare in the tropics. There is a significant linear negative correlation between the prevalence of activated BAT and the average outdoor temperature.