Regulating Drug Release Behavior and Kinetics from Matrix Tablets Based on Fine Particle-Sized Ethyl Cellulose Ether Derivatives: An In Vitro and In Vivo Evaluation

Table 1

Formulation of 200 mg ciprofloxacin HCl tablets.

Drug	D : P ratio	Polymer	Filler (lactose)	Lubricant (0.5%)
Ciprofloxacin HCl-ETHOCEL CR tablets
100 mg	10 : 01	10 mg	89 mg	1 mg
100 mg	10 : 02	20 mg	79 mg	1 mg
100 mg	10 : 03	30 mg	69 mg	1 mg
100 mg	10 : 04	40 mg	59 mg	1 mg
100 mg	10 : 05	50 mg	49 mg	1 mg
100 mg	10 : 06	60 mg	39 mg	1 mg
100 mg	10 : 07	70 mg	29 mg	1 mg
100 mg	10 : 08	80 mg	19 mg	1 mg