Table 3: Values of physicochemical parameters applied to CR tablets of ciprofloxacin HCl.

S/no.Parameter10 : 110 : 210 : 310 : 410 : 510 : 610 : 710 : 8

( 1 ) Weight variation (mg)202.3201.7199.8202.4200.9201.3203.4203.2
( 2 ) Friability (%) 0 . 3 1 ± 0 . 1 7 0 . 3 8 ± 0 . 2 1 0 . 3 4 ± 0 . 1 9 0 . 2 7 ± 0 . 0 9 0 . 3 9 ± 0 . 2 2 0 . 2 2 ± 0 . 0 7 0 . 1 7 ± 0 . 0 4 0 . 3 8 ± 0 . 2 1
( 3 ) Hardness (kg/cm2) 6 . 7 ± 0 . 1 3 6 . 4 ± 0 . 1 2 6 . 9 ± 0 . 1 6 6 . 8 ± 0 . 1 5 7 . 1 ± 0 . 1 8 6 . 9 ± 0 . 1 3 7 . 0 ± 0 . 1 7 6 . 8 ± 0 . 1 5
( 4 ) Diameter (mm) 8 ± 0 . 0 7 8 ± 0 . 0 5 8 ± 0 . 0 7 8 ± 0 . 0 7 8 ± 0 . 0 4 8 ± 0 . 0 6 8 ± 0 . 0 8 8 ± 0 . 0 7
( 5 ) Thickness (mm) 2 . 7 ± 0 . 0 9 2 . 7 ± 0 . 0 9 2 . 8 ± 0 . 0 8 2 . 6 ± 0 . 0 5 2 . 6 ± 0 . 0 6 2 . 7 ± 0 . 0 8 2 . 7 ± 0 . 0 6 2 . 5 ± 0 . 0 5
( 6 ) Drug content (%)98.397.8102.197.598.9101.399.598.7