Research Article

Dietary (n-6 : n-3) Fatty Acids Alter Plasma and Tissue Fatty Acid Composition in Pregnant Sprague Dawley Rats

Table 2

Plasma fatty acid composition (mg/100 mL; Mean ± SE; 𝑛 = 7 ) of rats from different treatment groups after 10 weeks of feeding.

Fatty acid composition(g/100 mL) of plasmaGroup
Diet (1 : 1)Diet (6 : 1)Diet (30 : 1)Diet (control)

C12 : 0 lauric acid2.25 ± 0.28a1.02 ± 0.16b1.84 ± 0.09a0.56 ± 0.19b
C14 : 0 myristic acid1.31 ± 0.33a1.19 ± 0.41aNd0.53 ± 0.11b
C15 : 0 pentadecanoic acid1.66 ± 0.30a1.67 ± 0.28a1.12 ± 0.19a0.41 ± 0.05b
C16 : 0 palmitic acid15.53 ± 0.80b12.04 ± 0.83b13.75 ± 1.07b21.67 ± 2.11a
C16 : 1 palmitoleic acid0.50 ± 0.05b0.94 ± 0.15ab0.72 ± 0.14ab1.27 ± 0.22a
C17 : 0 heptadecanoic acid 1 4 . 5 5 ± 0 . 3 6 ab14.76 ± 0.70a 1 3 . 8 3 ± 0 . 8 9 ab12.20 ± 0.90b
C18 : 0 stearic acid10.34 ± 0.90b8.93 ± 1.30b9.88 ± 1.42b14.93 ± 1.23a
C18 : 1 oleic acid 0 . 6 6 ± 0 . 0 5 ns 0 . 7 7 ± 0 . 1 0 ns 1 . 0 6 ± 0 . 2 3 ns 1 . 1 1 ± 0 . 2 4 ns
C18 : 2 n-6 linoleic acid 2 4 . 8 5 ± 0 . 9 5 ns 2 3 . 0 6 ± 1 . 4 5 ns 2 4 . 9 3 ± 2 . 4 8 ns 2 4 . 2 1 ± 1 . 0 2 ns
C20 : 0 arachidic acid 0 . 7 0 ± 0 . 0 4 ns 0 . 7 7 ± 0 . 1 1 ns 0 . 7 5 ± 0 . 1 0 nsNd
C20 : 4 n-6 arachidonic acid13.94 ± 1.32b 2 2 . 6 2 ± 1 . 6 6 a 2 3 . 4 3 ± 2 . 1 4 a 1 9 . 5 8 ± 2 . 4 2 ab
C20 : 5 n-3 eicosapentaenoic acid3.82 ± 0.72a3.05 ± 0.34ab1.73±0.58bNd
C22 : 5 n-3 docosapentaenoic acid0.90 ± 0.26a0.59 ± 0.24b0.32±0.14bNd
C22 : 6 n-3 docosahexaenoic acid6.49 ± 0.47a4.22 ± 0.57b4.33 ± 0.64b2.09 ± 0.15c
Total saturated37.32 ± 1.00a33.16 ± 0.42b33.19±0.77b36.48 ± 1.40a
Total unsaturated62.68 ± 1.00b66.84± 0.42a66.81 ± 0.77a63.52 ± 1.40b
Total monoenes12.69 ± 0.80b12.50 ± 1.51b12.88 ± 1.40b17.65 ± 1.14a
Total PUFA n-3 11.21 ± 0.49a7.85 ± 0.54b6.38 ± 1.00b 2 . 0 9 ± 0 . 1 5 c
Total PUFA n-6 3 8 . 7 9 ± 0 . 4 2 bc46.49 ± 1.54a47.55 ± 1.17a43.79 ± 1.51b
n-6 : n-3 ratio3.49 ± 0.17c6.05 ± 0.54bc8.79 ± 2.16b21.36 ± 1.44a
Unsat : Sat 1 . 6 9 ± 0 . 0 7 ns 2 . 0 2 ± 0 . 0 4 ns 2 . 0 2 ± 0 . 0 7 ns 1 . 7 6 ± 0 . 1 0 ns
Poly : Sat ratio1.34 ± 0.05b1.64 ± 0.06a1.63 ± 0.09a1.27 ± 0.08b

Values with different superscripts within rows are significantly different at 𝑃 < 0 . 0 5 ; nsno significant difference; ND: not detected.