Correlation of Surgical Pleth Index with Stress Hormones during Propofol-Remifentanil Anaesthesia

Table 3

Stress hormones levels, mean Bp, heart rate, SPI, and BIS values at the different event-related time points.

Time point	Group	ACTH; (pg/mL)	Cortisol; (pg/mL)	Epinephrine; (pg/mL)	Norepinephrine; (pg/mL)	Mean; (mmHg)	HR; (beat/min)	SPI	BIS
Base	SSI	23 ± 14	14 ± 5	38 ± 18	187 ± 114	94 ± 14	71 ± 13	53 ± 11	92 ± 15
	Control	19 ± 13	13 ± 6	34 ± 18	252 ± 172	99 ± 14	70 ± 12	53 ± 11	97 ± 2
Intu	SSI	15 ± 7**	10 ± 4**	28 ± 19	129 ± 69**	94 ± 20	72 ± 12	51 ± 13	37 ± 10**
	Control	16 ± 9	11 ± 4*	26 ± 9	132 ± 73**	93 ± 16	75 ± 15	53 ± 14	37 ± 13**
Maxi	SSI	10 ± 5^**#	8 ± 4^**##	34 ± 17	83 ± 50^**##	74 ± 10^**##	59 ± 10^**##	43 ± 12^**##	39 ± 11**
	Control	11 ± 65^**#	8 ± 3^**##	35 ± 24^#	82 ± 49^**#	77 ± 16^**##	59 ± 10^**##	45 ± 14^*#	38 ± 9**
After-Maxi	SSI	9 ± 6^**##	5 ± 3^**##&	19 ± 18^**#&&	35 ± 19^**##&&	77 ± 13^**##	59 ± 9^**##	29 ± 11^**##&&	44 ± 11**
	Control	9 ± 5^**##	6 ± 4^**##	19 ± 10^**&&	36 ± 18^**##&	82 ± 15^**##	58 ± 10^**##	31 ± 13^**##&&	40 ± 7**

Values are mean ± SD. Base = baseline before anaesthesia; Intu = after tracheal intubation; Max = at maximum operative trauma which defined intraoperatively by the surgeon; After-Max = 15 min after the maximum operative trauma; SSI = the group in which remifentanil administration was guided by SSI; Control = the group in which remifentanil administration was guided by standard traditional inadequate anaesthesia criteria.
* P < 0.05, **P < 0.01 compare with respective values at Base in the same group with one-way ANOVA followed by LSD test.
^#P < 0.05, ^##P < 0.01 compared with respective values at Intu in the same group with one-way ANOVA followed by LSD test.
^&P < 0.05, ^&&P < 0.01 compared with respective values at Maxi in the same group with one-way ANOVA followed by LSD test.
No any differences were found at all four event-related timepoints between the SPI group and the Control group (P > 0.05).