Clinical Study
The Association between Single-Nucleotide Polymorphisms of ORAI1 Gene and Breast Cancer in a Taiwanese Population
Table 3
Genotyping and allele frequency of ORAI1ββgene in patients with breast cancer with different progesterone receptor (PR) status.
| | | Positive (%) | Negative (%) | | Positive (%) | Negative (%) | Dominant | Recessive | Allelic | | Genotype | () | () | Allele | () | () | P value | P value | P value |
| | rs12320939 | TT | 52 (24.1) | 23 (15.3) | T | 210 (48.6) | 129 (43.0) | 0.6025 | 0.0416
*
| 0.1343 | | TG | 106 (49.1) | 83 (55.3) | G | 222 (51.4) | 171 (57.0) | | | | | GG | 58 (26.8) | 44 (29.4) | | | | | | | | rs12313273 | CC | 16 (7.5) | 6 (3.9) | C | 119 (27.8) | 73 (23.9) | 0.4110 | 0.1572 | 0.2302 | | CT | 87 (40.6) | 61 (39.9) | T | 309 (72.2) | 233 (76.1) | | | | | TT | 111 (51.9) | 86 (56.2) | | | | | | | | rs7135617 | TT | 31 (14.8) | 26 (17.7) | T | 166 (39.7) | 136 (46.3) | 0.0401
*
| 0.4696 | 0.0819 | | TG | 104 (49.8) | 84 (57.1) | G | 252 (60.3) | 158 (53.7) | | | | | GG | 74 (35.4) | 37 (25.2) | | | | | | | | rs6486795 | CC | 27 (12.7) | 14 (9.4) | C | 156 (36.6) | 105 (35.2) | 0.9220 | 0.3325 | 0.7025 | | CT | 102 (47.9) | 77 (51.7) | T | 270 (63.4) | 193 (64.8) | | | | | TT | 84 (39.4) | 58 (38.9) | | | | | | | | rs712853 | CC | 24 (11.2) | 12 (7.8) | C | 149 (34.8) | 91 (29.7) | 0.1976 | 0.2843 | 0.1485 | | CT | 101 (47.2) | 67 (43.8) | T | 279 (65.2) | 215 (70.3) | | | | | TT | 89 (41.6) | 74 (48.4) | | | | | | |
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|
*
is labeled in bold.
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