Biology and Biotechnology of Follicle Development

Table 4

Localization of EGF, TGF-α, EGF-R proteins and mRNA in the bovine ovary [28].

Cell type	EGF	EGF-r	TGF-α	EGF		EGF-r		TGF-α
				Prot.	RNA	Prot.	RNA	Prot.	RNA
Oocyte	+	+	+	+	—	+	(+)	+	(+)
Cumulus	+	+	+	+	(+)	+	+	+	(+)
Granulosa	+	+	+	+	(+)	+	+	+	+
Theca	—	—	+	—	—	—	+	+	+
	Preantral follicles			Antral follicles

EGF: epidermal growth factor, EGF-r: EGF receptor; TGF-α: transforming growth factor alpha, +: yes; —: no; Prot.: proteins.