Clinical Study

Reinstitution of Mechanical Ventilation within 14 Days as a Poor Predictor in Prolonged Mechanical Ventilation Patients following Successful Weaning

Table 1

Clinical characteristics of 142 prolonged mechanical ventilation patients following weaning and comparison between the reinstitution within 14 days and beyond 14 days.

VariablesTotal subjects 𝑁 = 1 4 2 Reinstitution within 14 days 𝑁 = 2 7 Reinstitution beyond 14 days 𝑁 = 1 1 5 P

Age (year) 6 8 . 7 ± 1 5 . 1 7 1 . 0 ± 1 2 . 9 6 8 . 1 ± 1 5 . 6 0.38
Gender (M/F)79/6315/1264/510.99
Transfer origin MICU/SICU*113/2919/893/220.39

Initial causes of ARF
ARDS (%)27 (19.0)5 (18.5)22 (19.1)0.95
CHF (%)35 (24.6)5 (18.5)30 (24)0.65
COPD (%)16 (11.3)3 (11.1)13 (11.3)0.98
Neurologic disorder (%)13 (9.2)3 (11.1)11 (8)0.62
After operation (%)29 (20.4)5 (18.5)24 (20.8)0.89
Other (%)22 (15.5)4 (14.8)18 (15.6)0.89
Tracheostomy (%)56 (39.4)14(52)43 (37)0.21
Coma (%)65 (45.8)16 (61)48 (42)0.12
Length of stay in RCC (days) 1 7 . 0 ± 9 . 9 1 8 . 1 ± 1 0 . 7 1 6 . 7 ± 9 . 6 0.81
MV duration (days) 3 4 . 7 ± 1 5 . 6 4 0 . 2 ± 1 9 . 4 3 3 . 5 ± 1 4 . 3 0.04
RSBI 1 0 0 . 2 ± 4 6 . 3 1 0 9 . 6 ± 5 3 . 2 9 6 . 9 ± 4 3 . 7 0.14
APACHE II scores 1 6 . 3 ± 7 . 3 1 8 . 7 ± 7 . 4 1 5 . 7 ± 7 . 2 0.053

Underlying disease
Diabetes mellitus (%)56 (39.4)11 (41)45 (39)0.84
Hypertension (%)91 (64.1)18 (67)72 (63)0.74
RIFLE-LE (%)60 (42.3)18(67)15 (37)0.005
Stroke (%)47 (33.1)6 (22)41 (36)0.18
Liver cirrhosis (%)15 (10.6)4 (15)11 (10)0.19
COPD (%)73 (51.4)9 (33)58 (50)0.27

Blood cell count
WBC (103/cmm) 8 7 2 2 ± 8 1 6 8 . 8 ± 3 . 1 8 . 6 ± 4 . 0 0.92
Hemoglobin (g/dL) 1 0 . 6 ± 1 . 0 1 0 . 5 ± 0 . 9 1 0 . 7 ± 1 . 1 0.58
Hematocrit (%) 3 2 . 8 ± 3 . 5 3 1 . 9 ± 2 . 3 3 3 . 6 ± 4 . 4 0.30
Platelet (104/cmm) 1 9 . 0 ± 1 . 9 1 7 . 5 ± 5 . 6 2 0 . 5 ± 9 . 5 0.48

Blood chemistry
Na (meq/L) 1 3 5 ± 2 . 3 1 3 6 ± 1 . 8 1 3 5 ± 2 . 6 0.34
K (meq/L) 4 . 1 ± 0 . 4 4 . 0 ± 0 . 6 4 . 2 ± 0 . 3 0.44
BUN (meq/L) 4 7 . 6 ± 1 1 . 0 5 3 . 0 6 ± 2 0 . 0 4 2 . 9 ± 1 2 . 3 0.66
CR (mg/L) 1 . 9 ± 0 . 5 2 . 2 ± 0 . 9 1 . 6 ± 0 . 6 0.53
Albumin (g/dL) 2 . 3 ± 0 . 6 2 . 4 ± 0 . 5 2 . 2 ± 0 . 7 0.32

Classification of renal diseases by the RIFLE criteria (acronym indicating risk of renal dysfunction, injury to the kidney, failure of kidney function, loss of kidney function, and end-stage kidney disease). MICU/SICU: medical intensive care unit/surgical intensive care unit.