Research Article

Comparison of Epirubicin-Iodized Oil Suspension and Emulsion for Transcatheter Arterial Chemoembolization in VX2 Tumor

Figure 2

Sonazoid-enhanced ultrasonographic and histopathological examination. (a) Immediately after Sonazoid administration, the tumor shows a strong contrast effect, depending on the vascular distribution, particularly in the marginal area (arrowheads). (b) While the tumor lacks a contrast effect 10 min after administration of Sonazoid (the Kupffer phase), the edge can be clearly visualized (arrows). (c) Cellular colonies with adequately stained nuclei and cytoplasm can be observed in the viable (c) but not the necrotic portion (d). A deposit of iodized oil (I) remains in the destroyed vascular structure (e). (c–e): hematoxylin-eosin staining, 20x original magnification.
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(a)
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(b)
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(c)
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(d)
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(e)