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The Scientific World Journal
Volume 2012 (2012), Article ID 962951, 8 pages
http://dx.doi.org/10.1100/2012/962951
Research Article

Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients

1Section for Social Pharmacy, University of Copenhagen, Jagtvej 160, 1st Floor, 2400 Copenhagen, Denmark
2Department of Oncology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
3Department of Cardiology and Endocrinology, Hillerød University Hospital, Dyrehavevej 29, 3400 Hillerød, Denmark
4Department of Integrated Healthcare, Bispebjerg University Hospital, Bispebjerg Bakke 11 B, 2400 Copenhagen, Denmark

Received 27 October 2011; Accepted 9 January 2012

Academic Editor: Mario D. Galigniana

Copyright © 2012 Ramune Jacobsen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The main aim of the study was to identify predictors of the effects of lifestyle intervention on diabetes mellitus type 2 patients by means of multivariate analysis. Data from a previously published randomised clinical trial, which compared the effects of a rehabilitation programme including standardised education and physical training sessions in the municipality’s health care centre with the same duration of individual counseling in the diabetes outpatient clinic, were used. Data from 143 diabetes patients were analysed. The merged lifestyle intervention resulted in statistically significant improvements in patients’ systolic blood pressure, waist circumference, exercise capacity, glycaemic control, and some aspects of general health-related quality of life. The linear multivariate regression models explained 45% to 80% of the variance in these improvements. The baseline outcomes in accordance to the logic of the regression to the mean phenomenon were the only statistically significant and robust predictors in all regression models. These results are important from a clinical point of view as they highlight the more urgent need for and better outcomes following lifestyle intervention for those patients who have worse general and disease-specific health.