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The Scientific World Journal
Volume 2013, Article ID 124315, 4 pages
Research Article

Quality of Life in Patients with Minimal Change Nephrotic Syndrome

1Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Aomori, Hirosaki-shi 036 8564, Japan
2Department of Cardiology, Respiratory Medicine and Nephrology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Aomori, Hirosaki-shi, 036 8562, Japan

Received 18 January 2013; Accepted 5 February 2013

Academic Editors: A. Bagul and B. R. Di Iorio

Copyright © 2013 Yoshiko Shutto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aim. The goal of the study was to investigate quality of life (QOL) in adult patients with minimal change nephrotic syndrome (MCNS) and to test the relationship of QOL with the level of self-care. Materials and Methods. We distributed two questionnaires to 30 outpatients with MCNS. The MOS 36-item Short Form Health Survey (SF-36v2) was used to examine health-related QOL in comparison with normative data from the general Japanese population and a population with two chronic diseases. SF-36v2 consists of 36 questions classified into 8 subscales. We also used the Self-Care Behavior Scale for patients with chronic kidney disease (CKD), which consists of 31 questions with 4 subscales. Results. The SF-36v2 social functioning subscale was most impaired and bodily pain was least affected in patients with MCNS. The self-care subscales of information/communication and positive behavior had positive correlations with the QOL subscales of mental health ( ) and vitality ( ). The correlation between social functioning and information/communication was close to significant ( ). Conclusion. In MCNS, social functioning was particularly impaired. Our results suggest that better self-care can have a positive impact on QOL in patients with MCNS.