Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2013, Article ID 125027, 7 pages
http://dx.doi.org/10.1155/2013/125027
Research Article

Evaluation of Antioxidant, Immunomodulatory, and Cytotoxic Action of Fractions from Eugenia uniflora L. and Eugenia malaccensis L.: Correlation with Polyphenol and Flavanoid Content

1Laboratório de Glicoproteínas, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco, Avenida Professor Moraes Rêgo s/n, Cidade Universitária, 50670-420 Recife, PE, Brazil
2Laboratório de Imunoparasitologia, Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz/PE, Avenida Professor Moraes Rego s/n, Cidade Universitária, 50670-420 Recife, PE, Brazil
3Laboratório de Produtos Naturais, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Pernambuco, Avenida Professor Moraes Rêgo s/n, Cidade Universitária, 50670-420 Recife, PE, Brazil

Received 31 May 2013; Accepted 29 June 2013

Academic Editors: F. A. Simmen and A. Surguchov

Copyright © 2013 Evellyne de Oliveira Figueirôa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. G. Faqueti, C. M. Petry, C. Meyre-Silva et al., “Euglobal-like compounds from the genus Eugenia,” Natural Product Research, vol. 27, no. 1, pp. 28–31, 2013. View at Publisher · View at Google Scholar
  2. A. G. Amat and M. E. Yajía, “Medicinal plants and ethnopharmacology in the province of Misiones (Argentina),” Acta Farmaceutica Bonaerense, vol. 10, no. 3, pp. 153–159, 1991. View at Google Scholar · View at Scopus
  3. E. E. Ratera and M. O. Ratera, Plantas de la Flora Argentina empleadas en Medicina Popular, Hemisferio Sul, Buenos Aires, Argentina, 1980.
  4. A. E. Consolini, O. A. N. Baldini, and A. G. Amat, “Pharmacological basis for the empirical use of Eugenia uniflora L. (Myrtaceae) as antihypertensive,” Journal of Ethnopharmacology, vol. 66, no. 1, pp. 33–39, 1999. View at Publisher · View at Google Scholar · View at Scopus
  5. C. E. Almeida, M. G. O. Karnikowski, R. Foleto, and B. Baldisserotto, “Analysis of antidiarrhoeic effect of plants used in popular medicine,” Revista de Saude Publica, vol. 29, no. 6, pp. 428–433, 1995. View at Google Scholar · View at Scopus
  6. M. T. Auricchio, A. Bugno, S. B. M. Barros, and E. M. Bacchi, “Antimicrobial and antioxidant activities and toxicity of Eusenia uniflora,” Latin American Journal of Pharmacy, vol. 26, no. 1, pp. 76–81, 2007. View at Google Scholar · View at Scopus
  7. A. B. Joly, Botânica: Introdução à Taxonomia Vegetal, Companhia Editora Nacional, São Paulo, Brazil, 13th edition, 2002.
  8. K. Roosita, C. M. Kusharto, M. Sekiyama, Y. Fachrurozi, and R. Ohtsuka, “Medicinal plants used by the villagers of a Sundanese community in West Java, Indonesia,” Journal of Ethnopharmacology, vol. 115, no. 1, pp. 72–81, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. I. I. Mahmoud, M. S. A. Marzouk, F. A. Moharram, M. R. El-Gindi, and A. M. K. Hassan, “Acylated flavonol glycosides from Eugenia jambolana leaves,” Phytochemistry, vol. 58, no. 8, pp. 1239–1244, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. I. Lunardi, J. L. B. Peixoto, C. C. da Silva, I. T. A. Shuquel, E. A. Basso, and G. J. Vidotti, “Triterpenic acids from Eugenia moraviana,” Journal of the Brazilian Chemical Society, vol. 12, no. 2, pp. 180–183, 2001. View at Google Scholar · View at Scopus
  11. R. N. Oliveira, I. J. M. Dias, and C. A. G. Câmara, “Estudo comparativo do óleo essencial de Eugenia punicifolia (HBK) DC. de diferentes localidades de Pernambuco,” Revista Brasileira de Farmacognosia, vol. 15, pp. 39–43, 2005. View at Google Scholar
  12. H. S. Falcão, I. O. Lima, V. L. Santos et al., “Review of the plants with anti-inflammatory activity studied in Brazil,” Revista Brasileira de Farmacognosia, vol. 15, pp. 381–391, 2005. View at Google Scholar
  13. I. O. Lima, R. A. G. Oliveira, E. O. Lima, N. M. P. Farias, and E. L. Souza, “Atividade antifúngica de óleos essenciais sobre espécies de Candida,” Revista Brasileira de Farmacognosia, vol. 16, pp. 197–201, 2006. View at Google Scholar
  14. K. Ravi, S. Rajasekaran, and S. Subramanian, “Antihyperlipidemic effect of Eugenia jambolana seed kernel on streptozotocin-induced diabetes in rats,” Food and Chemical Toxicology, vol. 43, no. 9, pp. 1433–1439, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. J. M. Barbosa-Filho, T. H. C. Vasconcelos, A. A. Alencar et al., “Plants and their active constituents from South, Central, and North America with hypoglycemic activity,” Revista Brasileira de Farmacognosia, vol. 15, pp. 392–413, 2005. View at Google Scholar
  16. E. Velázquez, H. A. Tournier, P. M. de Buschiazzo, G. Saavedra, and G. R. Schinella, “Antioxidant activity of Paraguayan plant extracts,” Fitoterapia, vol. 74, no. 1-2, pp. 91–97, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. V. L. Singleton and J. A. Rossi, “Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents,” The American Journal of Enology and Viticulture, vol. 16, pp. 144–158, 1965. View at Google Scholar
  18. R. G. Woisky and A. Salatino, “Analysis of propolis: some parameters and procedures for chemical quality control,” Journal of Apicultural Research, vol. 37, no. 2, pp. 99–105, 1998. View at Google Scholar · View at Scopus
  19. W. Brand-Williams, M. E. Cuvelier, and C. Berset, “Use of a free radical method to evaluate antioxidant activity,” LWT—Food Science and Technology, vol. 28, no. 1, pp. 25–30, 1995. View at Google Scholar · View at Scopus
  20. Y. L. C. de Oliveira, L. C. N. da Silva, A. G. da Silva et al., “Antimicrobial activity and phytochemical screening of Buchenavia tetraphylla (Aubl.) RA Howard, (Combretaceae: Combretoideae),” The Scientific World Journal, vol. 2012, Article ID 849302, 6 pages, 2012. View at Publisher · View at Google Scholar
  21. V. R. A. Pereira, V. M. B. Lorena, A. P. G. da Silva et al., “Immunization with cytoplasmic repetitive antigen and flagellar repetitive antigen of Trypanosoma cruzi stimulates a cellular immune response in mice,” Parasitology, vol. 129, no. 5, pp. 563–570, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Guleria, A. K. Tiku, A. Koul, S. Gupta, G. Singh, and V. K. Razdan, “Antioxidant and antimicrobial properties of the essential oil and extracts of Zanthoxylum alatum grown in North-Western Himalaya,” The Scientific World Journal, vol. 2013, Article ID 790580, 9 pages, 2013. View at Publisher · View at Google Scholar
  23. L. C. N. Silva, J. M. Sandes, M. M. Paiva et al., “Anti-Staphylococcus aureus action of three Caatinga fruits evaluated by electron microscopy,” Natural Product Research, 2012. View at Publisher · View at Google Scholar
  24. J. J. B. Jandú, L. C. N. Silva, A. P. C. Pereira et al., “Myracrodruon urundeuva bark: an antimicrobial, antioxidant and non-cytotoxic agent,” Journal of Medicinal Plants Research, vol. 7, pp. 413–418, 2013. View at Google Scholar
  25. P. G. Waterman and S. Mole, Analysis of Phenolic Plant Metabolites, Blackwell Scientific, Oxford, UK, 1994.
  26. L. C. N. da Silva, C. A. da Silva Jr., R. M. de Souza, A. José Macedo, M. V. da Silva, and M. T. S. Correia, “Comparative analysis of the antioxidant and DNA protection capacities of Anadenanthera colubrina, Libidibia ferrea and Pityrocarpa moniliformis fruits,” Food and Chemical Toxicology, vol. 49, no. 9, pp. 2222–2228, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. T. Kalaivani, C. Rajasekaran, K. Suthindhiran, and L. Mathew, “Free radical scavenging, cytotoxic and hemolytic activities from leaves of Acacia nilotica (L.) Wild. ex. Delile subsp. indica (Benth.) Brenan,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 274741, 8 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. I. Vermes, C. Haanen, and C. Reutelingsperger, “Flow cytometry of apoptotic cell death,” Journal of Immunological Methods, vol. 243, no. 1-2, pp. 167–190, 2000. View at Publisher · View at Google Scholar · View at Scopus
  29. S. C. Shen, W. R. Lee, H. Y. Lin et al., “In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production,” European Journal of Pharmacology, vol. 446, no. 1–3, pp. 187–194, 2002. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Martínez-Flórez, B. Gutiérrez-Fernández, S. Sánchez-Campos, J. González-Gallego, and M. J. Tuñón, “Quercetin attenuates nuclear factor-κB activation and nitric oxide production in interleukin-1beta-activated rat hepatocytes,” Journal of Nutrition, vol. 135, no. 6, pp. 1359–1365, 2005. View at Google Scholar
  31. H. J. Park, C. M. Lee, I. D. Jung et al., “Quercetin regulates Th1/Th2 balance in a murine model of asthma,” International Immunopharmacology, vol. 9, no. 3, pp. 261–267, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. C. Y. Li, J. L. Suen, B. L. Chiang, P. D. L. Chao, and S. H. Fang, “Morin promotes the production of Th2 cytokine by modulating bone marrow-derived dendritic cells,” The American Journal of Chinese Medicine, vol. 34, no. 4, pp. 667–684, 2006. View at Publisher · View at Google Scholar · View at Scopus