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The Scientific World Journal
Volume 2013, Article ID 135142, 7 pages
http://dx.doi.org/10.1155/2013/135142
Research Article

The Effects of Two Lactobacillus plantarum Strains on Rat Lipid Metabolism Receiving a High Fat Diet

1Institute of Experimental Medicine, Faculty of Medicine, P. J. Šafárik University, Trieda SNP 1, 040 01 Košice, Slovakia
2Department of Medical and Clinical Biochemistry, Faculty of Medicine, P. J. Šafárik University, Trieda SNP 1, 040 01 Košice, Slovakia
3Department of Cardiovascular Diseases, International Clinical Research Center, St. Anne’s Faculty Hospital, Masaryk University, Pekařská 53, 656 91 Brno, Czech Republic

Received 30 October 2013; Accepted 25 November 2013

Academic Editors: J. S. Marchini and A. Turrini

Copyright © 2013 Rastislav Salaj et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of our study was to evaluate the effects of the different probiotic strains, Lactobacillus plantarum LS/07 and Lactobacillus plantarum Biocenol LP96, on lipid metabolism and body weight in rats fed a high fat diet. Compared with the high fat diet group, the results showed that Lactobacillus plantarum LS/07 reduced serum cholesterol and LDL cholesterol, but Lactobacillus plantarum Biocenol LP96 decreased triglycerides and VLDL, while there was no change in the serum HDL level and liver lipids. Both probiotic strains lowered total bile acids in serum. Our strains have no significant change in body weight, gain weight, and body fat. These findings indicate that the effect of lactobacilli on lipid metabolism may differ among strains and that the Lactobacillus plantarum LS/07 and Lactobacillus plantarum Biocenol LP96 can be used to improve lipid profile and can contribute to a healthier bowel microbial balance.