Water-Protein Interactions: The Secret of Protein Dynamics

Table 1

Water non-selective and selective proton spin-lattice relaxation times as a function of the human albumin content at 298 K. In the same table the protein contribution to the selective and non-selective proton spin-lattice relaxation rates Δ𝑅₁^SE and Δ𝑅₁^NS is also reported.

Albumin concentration	Albumin concentration	𝑇^NS1	𝑇^SE1	𝑅^NS1	𝑅^SE1	Δ𝑅^NS1	Δ𝑅^SE1
mol/L	mg/mL	s	s	s^−1	s^−1	s^−1	s^−1
0	0	10.10	10.30	0.099	0.097	0	0
1.6×10^−5	1.0	8.30	6.45	0.120	0.155	0.021	0.058
3.2×10^−5	2.0	7.10	4.55	0.141	0.220	0.042	0.123
4.8×10^−5	3.0	6.15	3.60	0.163	0.278	0.064	0.181
6.5×10^−5	4.0	5.50	2.90	0.182	0.345	0.083	0.248
7.3×10^−5	4.5	5.10	2.70	0.196	0.370	0.097	0.273
8.1×10^−5	5.0	4.70	2.45	0.213	0.408	0.114	0.311
8.9×10^−5	5.5	4.45	2.30	0.225	0.435	0.126	0.338
9.7×10^−5	6.0	4.15	2.10	0.241	0.476	0.142	0.379
1.3×10^−4	8.0	3.55	1.66	0.282	0.602	0.183	0.505
1.6×10^−4	10.0	3.10	1.40	0.323	0.714	0.202	0.559