Research Article

Risk of Coronary Heart Disease among HIV-Infected Patients: A Multicenter Study in Brazil

Table 3

Risk factors for intermediate and Framingham risk score among HIV-infected patients from Brazil.

RR (95% CI) value

Study site in Brazil*0.12
 Northeast1.0
 Midwestern0.8 (0.4–1.4)
 Southern0.7 (0.5–0.9)
Sex*<0.001
 Men1.0
 Women3.0 (2.1–4.2)
Age (years)*<0.001
 <501.0
 50–5916.3 (10.8–24.7)
 ≥6043.4 (28.5–66.0)
Skin color*0.7
 Nonwhite1.0
 White1.1 (0.8–1.4)
Years at school*0.9
 <101.0
 ≥101.0 (0.7–1.4)
Lifetime smoking*<0.001
 No1.0
 Yes2.2 (1.6–3.0)
Physical activity*0.9
 No1.0
 Yes1.0 (0.7–1.4)
Binge drinking*0.04
 No1.0
 Yes0.6 (0.4–1.0)
Current or past cocaine use*0.13
 No1.0
 Yes0.6 (0.3–1.2)
Body mass index (kg/m2)*<0.001
 ≤25.01.0
 25.0–29.91.3 (0.9–1.8)
 ≥30.02.3 (1.5–3.4)
Waist circumference (cm)*0.001
 <102/881.0
 ≥102/881.7 (1.3–2.4)
Hypertension status**<0.001
 Normal1.0
 Prehypertension2.1 (1.2–3.6)
 Hypertension4.6 (2.7–7.9)
Diabetes mellitus**<0.001
 No1.0
 Yes4.7 (3.4–6.5)
Antiretroviral use*0.7
 No1.0
 Yes0.9 (0.7–1.3)
Time since HIV diagnosis (years)*0.6
 <81.0
 8–290.8 (0.4–1.4)

Risk ratio was adjusted for study site, sex, age, years at school, smoking, binge drinking, cocaine use, antiretroviral use, and length of the HIV diagnosis.
**Risk ratio additionally adjusted for waist circumference, hypertension, and diabetes mellitus.