Risk of Coronary Heart Disease among HIV-Infected Patients: A Multicenter Study in Brazil
Table 3
Risk factors for intermediate and Framingham risk score among HIV-infected patients from Brazil.
RR (95% CI)
value
Study site in Brazil*
0.12
Northeast
1.0
Midwestern
0.8 (0.4–1.4)
Southern
0.7 (0.5–0.9)
Sex*
<0.001
Men
1.0
Women
3.0 (2.1–4.2)
Age (years)*
<0.001
<50
1.0
50–59
16.3 (10.8–24.7)
≥60
43.4 (28.5–66.0)
Skin color*
0.7
Nonwhite
1.0
White
1.1 (0.8–1.4)
Years at school*
0.9
<10
1.0
≥10
1.0 (0.7–1.4)
Lifetime smoking*
<0.001
No
1.0
Yes
2.2 (1.6–3.0)
Physical activity*
0.9
No
1.0
Yes
1.0 (0.7–1.4)
Binge drinking*
0.04
No
1.0
Yes
0.6 (0.4–1.0)
Current or past cocaine use*
0.13
No
1.0
Yes
0.6 (0.3–1.2)
Body mass index (kg/m2)*
<0.001
≤25.0
1.0
25.0–29.9
1.3 (0.9–1.8)
≥30.0
2.3 (1.5–3.4)
Waist circumference (cm)*
0.001
<102/88
1.0
≥102/88
1.7 (1.3–2.4)
Hypertension status**
<0.001
Normal
1.0
Prehypertension
2.1 (1.2–3.6)
Hypertension
4.6 (2.7–7.9)
Diabetes mellitus**
<0.001
No
1.0
Yes
4.7 (3.4–6.5)
Antiretroviral use*
0.7
No
1.0
Yes
0.9 (0.7–1.3)
Time since HIV diagnosis (years)*
0.6
<8
1.0
8–29
0.8 (0.4–1.4)
Risk ratio was adjusted for study site, sex, age, years at school, smoking, binge drinking, cocaine use, antiretroviral use, and length of the HIV diagnosis.
**Risk ratio additionally adjusted for waist circumference, hypertension, and diabetes mellitus.