The Scientific World Journal / 2013 / Article / Tab 2

Research Article

Tumor Necrosis Factor-Alpha Gene Promoter Region Polymorphism and the Risk of Coronary Heart Disease

Table 2

Genotype and allele frequencies of the TNF-α gene −1031T>C and −863C>A polymorphisms in the study population.

TNF- SNPControls ( )Patients ( )OR95% CIP valuea

−1031T/C
 TT182 (58.71%)178 (57.42%)1.050.76–1.450.8
 TC + CC128 (41.29%)132 (42.58%)
 T474 (76.45%)462 (74.52%)1.110.85–1.430.46
 C146 (23.55%)158 (25.48%)
−863C/A
 CC201 (64.84%)92 (29.68%)4.373.11–6.12 <
 CA + AA109 (35.16%)218 (70.32%)
 C503 (81.13%)399 (64.35%)2.381.83–3.08 <
 A117 (18.87%)221 (35.65%)

Values are given in numbers and percentage.
P value calculated by Chi-square test.
P value (<0.05) indicates statistical significance.
Odds ratio.
95% confidence intervals.

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