The Antinociceptive and Anti-Inflammatory Activities of Aspidosperma tomentosum (Apocynaceae)

Table 5

Effects of extract, fractions (100 mg/kg, p.o.), and isorhamnetin (100 μmol/kg, p.o.) in the thioglycolate-induced peritonitis.

Group	𝑛	Cell number × 10^6/mL	% of inhibition
		Mean ± S.E.M.	Mean ± S.E.M.
Vehicle	6	1.5 ± 1.0	—
CEE	6	3.6±0.4	57.6%**
Isorhamnetin	6	4.6±0.6	45.9%**
Soluble phase	6	2.2±0.3	74.1%**
Hexane 100%	6	3.4±0.4	60.0%**
Hex : CHCl3 50%	6	1.7±0.2	80.0%**
CHCl3 100%	6	3.8±0.5	55.3%**
CHCl3 : EtAcO 50%	6	3.2±0.6	62.3%**
EtAcO 100%	6	8.6±1.8	0.0%
CHCl3 : MeOH 5%	6	2.4±0.5	71.8%**
CHCl3 : MeOH 10%	6	4.6±0.5	45.9%**

Statistical differences between the treated and the control groups were evaluated by ANOVA and Dunnett tests, and the asterisks denote the significance levels in comparison with control groups, **𝑃<0.01.