Research Article
In Vitro Susceptibility of Candida Species to Four Antifungal Agents Assessed by the Reference Broth Microdilution Method
Table 2
MIC ranges as well as MIC50 and MIC90 values of the identified strains according to the antifungal agent.
| | Species () | Antifungal agent | MIC range (μg/mL) | (μg/mL) | (μg/mL) |
| | C. albicans (53) | Fluconazole | 0.25–32 | 0.5 | 16 | | Amphotericin B | 0.03–0.25 | 0.06 | 0.125 | | Voriconazole | 0.03–0.25 | 0.03 | 0.03 | | Caspofungin | 0.015–0.25 | 0.03 | 0.06 |
| | C. parapsilosis (41) | Fluconazole | 0.25–64 | 0.5 | 1 | | Amphotericin B | 0.03–0.25 | 0.06 | 0.125 | | Voriconazole | 0.03–0.06 | 0.03 | 0.03 | | Caspofungin | 0.06–0.25 | 0.125 | 0.25 |
| | C. tropicalis (3) | Fluconazole | 0.25–64 | 1 | 64 | | Amphotericin B | 0.125–0.25 | 0.125 | 0.25 | | Voriconazole | 0.03–16 | 0.06 | 16 | | Caspofungin | 0.015–0.06 | 0.06 | 0.06 |
| | C. krusei (6) | Fluconazole | 16–>64 | 64 | >64 | | Amphotericin B | 0.25–1 | 0.25 | 1 | | Voriconazole | 0.06–0.5 | 0.125 | 0.5 | | Caspofungin | 0.015–0.25 | 0.015 | 0.25 |
| | C. kefyr (2) | Fluconazole | 0.25–0.5 | 0.25 | 0.5 | | Amphotericin B | 0.125–0.5 | 0.125 | 0.5 | | Voriconazole | 0.03–0.03 | 0.03 | 0.03 | | Caspofungin | 0.03–0.06 | 0.03 | 0.06 |
| | C. glabrata (3) | Fluconazole | 16–>64 | 64 | >64 | | Amphotericin B | 0.125–0.125 | 0.125 | 0.125 | | Voriconazole | 0.25–2 | 1 | 2 | | Caspofungin | 0.015–0.06 | 0.03 | 0.06 |
| | C. lusitaniae (2) | Fluconazole | 0.5–2 | 0.5 | 2 | | Amphotericin B | 0.125–0.125 | 0.125 | 0.125 | | Voriconazole | 0.03 | 0.03 | 0.03 | | Caspofungin | 0.06–0.06 | 0.06 | 0.06 |
| | C. famata (1) | Fluconazole | 16 | 16 | 16 | | Amphotericin B | 0.25 | 0.25 | 0.25 | | Voriconazole | 0.25 | 0.25 | 0.25 | | Caspofungin | 0.03 | 0.03 | 0.03 |
|
|
