Research Article

Genotoxicity Assessment of Multispecies Probiotics Using Reverse Mutation, Mammalian Chromosomal Aberration, and Rodent Micronucleus Tests

Figure 3

The multispecies probiotic mixture does not induce increased number of micronucleated reticulocytes in mouse peripheral blood. (a) Body weight of mice before and 72 hours after ingestion of the test substance. (b) The number of reticulocytes in 1000 red blood cells from the peripheral blood of mice treated with control and test substance. (c) The number of micronucleated reticulocytes in 1000 reticulocytes. All graphs present mean ± SD ( ). RETs: reticulocytes; RBCs: red blood cells; Mn-RETs: micronucleated reticulocytes.
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(c)