The Scientific World Journal / 2013 / Article / Tab 2

Clinical Study

A Thirty-Year Follow-Up Surveillance Study for Neoplasia of a Dutch Ulcerative Colitis Cohort

Table 2

Cox regression analysis per independent factor.
(a) Positive for any dysplasia

FactorsNumber (%)UnivariateMultivariate
HR95% CISig.HR95% CISig.

Sex 1,5520.963–2.5020.0711,4300.878–2.3290.150
 Male45/148 (30.4)
 Female27/145 (18.6)
Location1,9221.115–3.3120.0191,9181.111–3.3110.019
 Pancolitis55/178 (30.9)
 Distal colitis17/115 (14.8)
Age at 1st surveillance, yrs1,0321.013–1.0510.0011,0281.009–1.0470.004

(b) Positive for HGD/CRC

FactorsNumber (%)UnivariateMultivariate
HR95% CISig.HR95% CISig.

Sex 1,3540.586–3.1290.4791,4600.624–3.4210.383
 Male14/148 (9.5)
 Female9/145 (6.2)
Location13,2321.783–98.1820.01213,5081.818–100.3840.011
 Pancolitis22/178 (12.4)
 Distal colitis1/115 (0.9)
Age at 1st
surveillance, yrs
1,0080.975–1.0420.6541,0020.968–1.0360.926

(c) Positive for CRC

FactorsNumber (%)UnivariateMultivariate
HR95% CISig.HR95% CISig.

Sex 0.7480.271–2.0640.5750.8740.310–2.4600.798
 Male7/148 (4.7)
 Female8/145 (5.5)
Location8,3051.092–63.1650.0418,4021.102–64.062 0.040
 Pancolitis14/178 (7.9)
 Distal colitis1/115 (0.9)
Age at 1st
surveillance, yrs
0.9860.943–1.0310.5310.9840.941–1.0290.486

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