Flaxseed Prevents Leukocyte and Platelet Adhesion to Endothelial Cells in Experimental Atherosclerosis by Reducing sVCAM-1 and vWF

Table 2

Mean ± SD values for platelet functions and endothelial markers in studied groups.

Measures	Sham	Sham + lard	Sham + lard + flaxseed	Ovx	Ovx + lard	Ovx + lard + flaxseed
Platelet functions
Aggregation (mOD/min)	7.9±1.2	21.0±1.3^b	14.6±1.3^bc	8.1±1.2	18.8±1.3^b	15.6±1.2^b
Adhesion (%)	29±6	34±3	31±4	31±7	40±9^b	34±4^c
Endothelial markers
sVCAM (ng/mL)	175±64	286±26^b	294±11^b	252±53^a	539±162^ab	404±10^ac
vWF (%)	111±6	118±6	104±10	178±13^a	193±16^ab	155±10^ac

Values are means ± SD, 𝑛=7 in each group.
 ^a𝑃<0.05 as compared to corresponding Sham groups.
 ^b𝑃<0.05 as compared to groups fed with low-fat diet.
 ^c𝑃<0.05 between lard and lard + flaxseed fed groups.