Studies of the Interaction between Isoimperatorin and Human Serum Albumin by Multispectroscopic Method: Identification of Possible Binding Site of the Compound Using Esterase Activity of the Protein

Table 4

Binding constants for isoimperatorin-HSA interaction (at 295 K) in the absence and presence of the site marker.

	𝐾𝑏×10^−5; (M^−1)	𝑅^a
HSA + isoimperatorin (in the absence of ibuprofen and warfarin)	11.10±0.4^∗	0.9947
HSA + isoimperatorin + ibuprofen	10.99±0.6^∗	0.9904
HSA + isoimperatorin + warfarin	7.89±0.3^∗	0.9881

Data are expressed as mean ± SD of three measurements.
^a𝑅 is the correlation coefficient for the 𝐾_𝑏 values. *𝑃value<0.0002.