Voluntary Exercise Prevents Lead-Induced Elevation of Oxidative Stress and Inflammation Markers in Male Rat Blood

Figure 5

Plasma tumor necrosis factor-𝛼 in sedentary control and exercise groups before and after lead administrations. Seven days of lead injections (15 mg/Kg body weight, ip) to sedentary animals housed in the regular cages caused significant increase of plasma TNF-𝛼 (*𝑃<0.05 compared to the “before lead administration”); in Ex animals housed in the wheel equipped cages, plasma TNF-𝛼 changes after the same dose lead administrations were not significant. The data are presented as means ± S.E.M. TNF-𝛼: tumor necrosis factor-𝛼; Sed Co: sedentary control group; Ex: exercise group.