The Scientific World Journal / 2013 / Article / Tab 2

Research Article

Extraction Optimization of Tinospora cordifolia and Assessment of the Anticancer Activity of Its Alkaloid Palmatine

Table 2

Central composite design by RSM program for optimization of extraction conditions with experimental and their corresponding predicted yields.

RunsExtraction temperature
( , °C)
Extraction time
( , hours)
Extraction cycles
( , cycle)
Experimental yield (%)Predicted yield (%)

140 (0)32 (0)12 (0)13.2911.51
250 (1)16 (−1)20 (1)8.168.86
340 (0)32 (0)12 (0)10.2611.51
430 (−1)48 (1)20 (1)11.3211.09
523.18 (−1.68)32 (0)12 (0)12.8913.09
656.82 (1.68)32 (0)12 (0)9.679.94
740 (0)5.09 (−1.68)12 (0)11.9311.51
840 (0)32 (0)−1.45 (−1.68)11.3611.91
950 (1)48 (1)4 (−1)12.1911.82
1040 (0)32 (0)25.45 (1.68)10.8311.12
1130 (−1)48 (1) 4 (−1)11.9711.20
1240 (0)32 (0)12 (0)11.3111.51
1330 (−1)16 (−1)04 (−1)13.6714.29
1450 (1)16 (−1) 04 (−1)9.539.68
1540 (0)58.91 (1.68)12 (0) 9.6711.52
1640 (0)32 (0)12 (0)12.7311.51
1750 (1)48 (1)20 (1)12.6511.96
1840 (0)32 (0)12 (0)12.4211.51
1930 (−1)16 (−1)20 (1)12.9213.21

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