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The Scientific World Journal
Volume 2013 (2013), Article ID 382350, 8 pages
http://dx.doi.org/10.1155/2013/382350
Research Article

Absorption and Metabolism Characteristics of Rutin in Caco-2 Cells

1Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaan’xi 710032, China
2Department of Otolaryngology, Shenyang 463 Hospital, Xiao He Yan Road 46, Shenyang, Liaoning 110042, China
3School of Pharmacy, Institute of Materia Medica, Fourth Military Medical University, Xi’an, Shaan’xi 710032, China

Received 17 July 2013; Accepted 25 August 2013

Academic Editors: M. Edery, S. E. Harris, R. B. Petersen, and M. Zarevucka

Copyright © 2013 Xiaofang Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Giovanni Lentini, and Solomon Habtemariam, “The therapeutic potential of rutin for diabetes: An update,” Mini-Reviews in Medicinal Chemistry, vol. 15, no. 7, pp. 524–528, 2015. View at Publisher · View at Google Scholar
  • Mi Hee Choi, Jong Kook Rho, Jung Ae Kang, Ha Eun Shim, You Ree Nam, Seonhye Yoon, Hye Rim Kim, Dae Seong Choi, Sang Hyun Park, Beom-Su Jang, and Jongho Jeon, “Efficient radiolabeling of rutin with I-125 and biodistribution study of radiolabeled rutin,” Journal Of Radioanalytical And Nuclear Chemistry, vol. 308, no. 2, pp. 477–483, 2016. View at Publisher · View at Google Scholar
  • Chun Wang, Wei Wei, Jun Yu, Peng Zhou, James Asenso, and Xiao-Dan Yang, “Advances in plant-based inhibitors of P-glycoprotein,” Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 31, no. 6, pp. 867–881, 2016. View at Publisher · View at Google Scholar
  • Mei Zeng, Lan Yang, Dan He, Yao Li, Mingxin Shi, and Jingqing Zhang, “Metabolic pathways and pharmacokinetics of natural medicines with low permeability,” Drug Metabolism Reviews, vol. 49, no. 4, pp. 464–476, 2017. View at Publisher · View at Google Scholar
  • Marcello Iriti, Robert Kubina, Andrea Cochis, Rita Sorrentino, Elena M. Varoni, Agata Kabała-Dzik, Barbara Azzimonti, Arkadiusz Dziedzic, Lia Rimondini, and Robert D. Wojtyczka, “Rutin, a Quercetin Glycoside, Restores Chemosensitivity in Human Breast Cancer Cells,” Phytotherapy Research, 2017. View at Publisher · View at Google Scholar
  • Mireille M.J.P.E. Sthijns, Paul M. Schiffers, Ger M. Janssen, Kristien J.A. Lemmens, Bart Ides, Philippe Vangrieken, Freek G. Bouwman, Edwin C. Mariman, Irina Pader, Elias S.J. Arnér, Katarina Johansson, Aalt Bast, and Guido R.M.M. Haenen, “Rutin protects against H 2 O 2 -triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress,” Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 1861, no. 5, pp. 1177–1189, 2017. View at Publisher · View at Google Scholar
  • Shima Sadeghi Ekbatan, Michele Iskandar, Lekha Sleno, Kebba Sabally, Joelle Khairallah, Satya Prakash, and Stan Kubow, “Absorption and Metabolism of Phenolics from Digests of Polyphenol-Rich Potato Extracts Using the Caco-2/HepG2 Co-Culture System,” Foods, vol. 7, no. 1, pp. 8, 2018. View at Publisher · View at Google Scholar