Sequential Oxygenation Index and Organ Dysfunction Assessment within the First 3 Days of Mechanical Ventilation Predict the Outcome of Adult Patients with Severe Acute Respiratory Failure
Table 4
Respiratory and ventilator parameters of survivors and nonsurvivors on day 1 and day 3 of mechanical ventilation#.
Day 1 and day 3 Respiratory and ventilator parameters
Characteristics
Hospital mortality
Survivor
values
Fi day1
0.66 (0.21)
0.53 (0.19)
0.002
Pa day 1 (mmHg)
163.02 (104.78)
126.63 (73.87)
0.14
PEEP* day 1 (mmHg)
5.95 (3.94)
5.31 (1.28)
0.38
mPaw* day 1 (mmHg)
12.16 (3.35)
11.89 (3.18)
0.69
PaO2/FiO2 day 1 (mmHg)
271.84 (184.39)
265.56 (180.55)
0.87
OI* day 1
7.81 (7.62)
6.59 (4.78)
0.33
FiO2 day 3
0.51 (0.21)
0.38 (0.1)
0.001
PaO2 day 3 (mmHg)
102.72 (42.17)
114.12 (24.94)
0.07
PEEP day 3 (cmH2O)
6.11 (3.71)
5.58 (1.66)
0.42
mPaw day 3 (cmH2O)
12.89 (3.42)
10.58 (2.38)
<0.001
PaO2/FiO2 day 3 (mmHg)
245.84 (144.83)
313.7 (86.32)
0.01
OI day 3 (cmH2O/mmHg)
8.82 (8.16)
3.86 (2.26)
<0.001
OI change from day 1 to day 3 (cmH2O/mmHg)
1.0 (8.446)
−2.74 (4.08)
<0.001
*FiO2: fraction inspired oxygen, mPaw: mean airway pressure, OI: oxygenation index, PaO2: arterial oxygen tension, PEEP: positive end-expiratory pressure. #Continuous variables were analyzed by Student’s t-test or Mann-Whitney U test, and categorical data by chi-square test. Variables are expressed as mean (standard deviation) and categorical data are expressed as number (percentage).
